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Background:
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
Applications:
ELISA, WB, IHC
Name of antibody:
SNRPA
Immunogen:
Full length fusion protein
Full name:
small nuclear ribonucleoprotein polypeptide A
Synonyms:
U1A; Mud1; U1-A
SwissProt:
P09012
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human lung cancer and human prostate cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
31 kDa
WB Positive control:
Human fetal liver tissue,A431 cell,293T cell,Hela cell , HEPG2 cell and A549 cell lysates
WB Recommended dilution:
500-2000