中文名稱: 兔抗SP1 (Phospho-Thr739)多克隆抗體
英文名稱: Anti-SP1 (Phospho-Thr739) rabbit polyclonal antibody
相關類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: SP1 (Phospho-Thr739)
反應種屬: Human Mouse Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規(guī)格
Background: |
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. |
Applications: |
WB |
Name of antibody: |
SP1 (Phospho-Thr739) |
Immunogen: |
Synthetic peptide of human SP1 (Phospho-Thr739) |
Full name: |
Sp1 transcription factor (Phospho-Thr739) |
SwissProt: |
P08047 |
WB Predicted band size: |
81 kDa |
WB Positive control: |
NIH/3T3 cells treated with serum starvation |
WB Recommended dilution: |
500-1000 |