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Background:
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue.
Applications:
ELISA, WB
Name of antibody:
TMPRSS2
Immunogen:
Fusion protein of human TMPRSS2
Full name:
transmembrane protease, serine 2
Synonyms:
PP9284; PRSS10
SwissProt:
O15393
ELISA Recommended dilution:
1000-2000
WB Predicted band size:
54 kDa
WB Positive control:
A549 cells
WB Recommended dilution:
200-1000