中文名稱: UACA 抗原(重組蛋白)
英文名稱: UACA Antigen (Recombinant Protein)
別 名: uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to C terminal 200 amino acids of human UACA
技術(shù)規(guī)格
Full name:
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uveal autoantigen with coiled-coil domains and ankyrin repeats
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Synonyms:
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NUCLING
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Swissprot:
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Q9BZF9
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Gene Accession:
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BC113407
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
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