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  • 產(chǎn)品名稱：ZNF217 抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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ZNF217 抗原（重組蛋白）關(guān)抗體在生物行業(yè)的發(fā)展國家給予了極大的重視，更多地側(cè)重于科研的投入，服務(wù)和業(yè)務(wù)在同行獲得一致好評，其立足于生命科學(xué)領(lǐng)域，全力打造高品質(zhì)生物科技產(chǎn)品鏈和技術(shù)服務(wù)鏈，也具備豐富的管理經(jīng)驗。
詳情介紹：

中文名稱： ZNF217 抗原（重組蛋白）


英文名稱： ZNF217 Antigen (Recombinant Protein)

別     名：  zinc finger protein 217; ZABC1

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原
 
概     述

Fusion protein corresponding to N terminal 200 amino acids of human ZNF217

技術(shù)規(guī)格

Full name:

zinc finger protein 217

Synonyms:

ZABC1

Swissprot:

O75362

Gene Accession:

BC113427

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ZNF217, also known as ZABC1, is a zinc finger protein belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and may play a role in transcriptional repression of a variety of genes through the recruitment of co-repressor complexes containing proteins such as CtBP, HDAC1 and HDAC2. In addition, ZNF217 participates in cell differentiation and appears to function as an oncogene. Expression of ZNF217 is amplified in various tumors and overexpression of the protein can attenuate apoptotic signals and lead to epithelial cell immortalization.Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.







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