別 名: aldehyde dehydrogenase 8 family, member A1;
ALDH12; DJ352A20.2
儲 存: 冷凍(-20℃)
概 述:
Full name: |
aldehyde dehydrogenase 8 family, member A1 |
Synonyms: |
ALDH12; DJ352A20.2 |
Swissprot: |
Q9H2A2 |
Gene Accession: |
BC113862 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. |
