英文名稱(chēng): Anti-RGS1 rabbit polyclonal antibody
別 名: 1R20; BL34; IER1; IR20; HEL-S-87
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RGS1
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
RGS1 |
Immunogen: |
Fusion protein of human RGS1 |
Full name: |
regulator of G-protein signaling 1 |
Synonyms: |
1R20; BL34; IER1; IR20; HEL-S-87 |
SwissProt: |
Q08116 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human prostate cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
RAW264.7 cells |
WB Recommended dilution: |
500-2000 |