英文名稱： Anti-RIC8A rabbit polyclonal antibody
別 名： RIC8 guanine nucleotide exchange factor A; RIC8
抗 原： RIC8A
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應種屬： Human, Mouse, Rat
相關類別： 一抗
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規(guī)格
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Background: |
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
RIC8A |
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Immunogen: |
Fusion protein of human RIC8A |
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Full name: |
RIC8 guanine nucleotide exchange factor A |
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Synonyms: |
RIC8 |
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SwissProt: |
Q9NPQ8 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human liver cancer |
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IHC Recommend dilution: |
50-300 |
