英文名稱: Anti-RNF111 rabbit polyclonal antibody
別 名: ring finger protein 111; ARK; hRNF111
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RNF111
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
RNF111 |
Immunogen: |
Fusion protein of human RNF111 |
Full name: |
ring finger protein 111 |
Synonyms: |
ARK; hRNF111 |
SwissProt: |
Q6ZNA4 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human gastric cancer |
IHC Recommend dilution: |
50-300 |
WB Predicted band size: |
109 kDa |
WB Positive control: |
TM4 cell lysate |
WB Recommended dilution: |
200-1000 |