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  • 產(chǎn)品名稱:兔抗RNF111多克隆抗體

  • 產(chǎn)品型號:100ul
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:1560
  • 產(chǎn)品庫存:60
  • 產(chǎn)品文檔:
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詳情介紹:
中文名稱:  兔抗RNF111多克隆抗體   

英文名稱: Anti-RNF111 rabbit polyclonal antibody

別      名: ring finger protein 111; ARK; hRNF111

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: RNF111

反應(yīng)種屬: Human, Mouse

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

RNF111

Immunogen:

Fusion protein of human RNF111

Full name:

ring finger protein 111

Synonyms:

ARK; hRNF111

SwissProt:

Q6ZNA4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

109 kDa

WB Positive control:

TM4 cell lysate

WB Recommended dilution:

200-1000






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