中文名稱:兔抗SDHB多克隆抗體
英文名稱: Anti-SDHB rabbit polyclonal antibody
別 名: IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: SDHB
反應種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SDHB |
Immunogen: |
Synthetic peptide of human SDHB |
Full name: |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
Synonyms: |
IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP |
SwissProt: |
P21912 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
32 kDa |
WB Positive control: |
293T cells and mouse brain tissue, human fetal liver tissue and hepg2 cells, Jurkat cells |
WB Recommended dilution: |
500-2000 |