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  • 產(chǎn)品名稱:兔抗SMURF2多克隆抗體

  • 產(chǎn)品型號:100ul
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:1560
  • 產(chǎn)品庫存:60
  • 產(chǎn)品文檔:
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詳情介紹:

中文名稱:  兔抗SMURF2多克隆抗體 

英文名稱: Anti-SMURF2 rabbit polyclonal antibody

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: SMURF2

反應種屬: Human, Mouse

標 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3.

Applications:

ELISA, IHC

Name of antibody:

SMURF2

Immunogen:

Synthetic peptide of human SMURF2

Full name:

SMAD specific E3 ubiquitin protein ligase 2

SwissProt:

Q9HAU4

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

25-100


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