中文名稱: 兔抗Synpr多克隆抗體
英文名稱: Anti-Synpr rabbit polyclonal antibody
別 名: synaptoporin
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: Synpr
反應(yīng)種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4). |
Applications: |
WB |
Name of antibody: |
Synpr |
Immunogen: |
Synthetic peptide of Rat Synpr |
Full name: |
Synpr |
Synonyms: |
synaptoporin |
SwissProt: |
P22831 |
WB Predicted band size: |
29 kDa |
WB Positive control: |
Rat brain and mouse brain |
WB Recommended dilution: |
500-1000 |