中文名稱: 兔抗TCF7多克隆抗體
英文名稱: Anti-TCF7 rabbit polyclonal antibody
別 名: transcription factor 7; TCF-1
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: TCF7
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. |
Applications: |
ELISA, IHC |
Name of antibody: |
TCF7 |
Immunogen: |
Synthetic peptide of human TCF7 |
Full name: |
transcription factor 7 |
Synonyms: |
TCF-1 |
SwissProt: |
P36402 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human lung cancer and Human prostate cancer |
IHC Recommend dilution: |
40-200 |