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  • 產(chǎn)品名稱：兔抗TEAD2多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫存：60
  • 產(chǎn)品文檔：
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上海通蔚生物科研實(shí)驗(yàn)所需的ELISA試劑盒，培養(yǎng)基，抗體，動(dòng)物血清血漿，標(biāo)準(zhǔn)品對(duì)照品，化學(xué)試劑，ELISA種屬涵蓋廣，憑借多年行業(yè)經(jīng)驗(yàn)，完善的售后服務(wù)，高質(zhì)量的產(chǎn)品，贏得客戶一致好評(píng)，兔抗TEAD2多克隆抗體歡迎來電咨詢與訂購！
詳情介紹：

中文名稱：  兔抗TEAD2多克隆抗體 

英文名稱： Anti-TEAD2 rabbit polyclonal antibody

別      名： TEA domain transcription factor 2; ETF; TEF4; TEF-4; TEAD-2

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃）

抗      原： TEAD2

宿      主： Rabbit

反應(yīng)種屬： Human, Mouse

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Applications:

ELISA, IHC

Name of antibody:

TEAD2

Immunogen:

Fusion protein of human TEAD2

Full name:

TEA domain transcription factor 2

Synonyms:

ETF; TEF4; TEF-4; TEAD-2

SwissProt:

Q15562

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

40-200


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