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  • 產(chǎn)品名稱：兔抗TESC多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：1560
  • 產(chǎn)品庫存：60
  • 產(chǎn)品文檔：
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上海通蔚生物科研實(shí)驗(yàn)所需的ELISA試劑盒，培養(yǎng)基，抗體，動物血清血漿，標(biāo)準(zhǔn)品對照品，化學(xué)試劑，ELISA種屬涵蓋廣，憑借多年行業(yè)經(jīng)驗(yàn)，完善的售后服務(wù)，高質(zhì)量的產(chǎn)品，贏得客戶一致好評，兔抗TESC多克隆抗體 歡迎來電咨詢與訂購！
詳情介紹：

中文名稱：  兔抗TESC多克隆抗體 

英文名稱： Anti-TESC rabbit polyclonal antibody

別      名： TSC; CHP3

相關(guān)類別： 一抗

儲      存： 冷凍（-20℃）

抗      原： TESC

宿      主： Rabbit

反應(yīng)種屬： Human, Mouse

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Tescalcin, also known as TESC, TSC or CHP3, is a 267 amino acid protein that contains one EF-hand domain and is expressed abundantly in ***** heart tissue. Using calcium as a cofactor, Tescalcin interacts with NHE-1 and functions to couple the activation of the ERK cascade with the expression of Ets proteins during megakaryocytic differentiation. Human Tescalcin shares 97% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of Tescalcin exist due to alternative splicing events. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Applications:

ELISA, IHC

Name of antibody:

TESC

Immunogen:

Fusion protein of human TESC

Full name:

tescalcin

Synonyms：

TSC; CHP3

SwissProt:

Q96BS2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human tonsil

IHC Recommend dilution:

25-100


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