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  • 產(chǎn)品名稱:SELENOF 抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:

中文名稱: SELENOF 抗原(重組蛋白)

英文名稱: SELENOF Antigen (Recombinant Protein)

別    名:   selenoprotein F; SEP15

相關(guān)類別: 抗原

儲    存:   冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 97-165 amino acids of human SELENOF

技術(shù)規(guī)格

Full name:

selenoprotein F

Synonyms:

SEP15

Swissprot:

O60613

Gene Accession:

BC005294

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.





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