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  • 產(chǎn)品名稱:TMEM123 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
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詳情介紹:

中文名稱: TMEM123 抗原(重組蛋白)

英文名稱: TMEM123 Antigen (Recombinant Protein)

別     名:  transmembrane protein 123; KCT3; PORMIN; PORIMIN

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to a region derived from 27-166 amino acids of human TMEM123

技術規(guī)格

Full name:

transmembrane protein 123

Synonyms:

KCT3; PORMIN; PORIMIN

Swissprot:

Q8N131

Gene Accession:

BC032296

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.





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