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  • 產(chǎn)品名稱：UBAP2L 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
UBAP2L 抗原（重組蛋白）為了適應(yīng)市場需要和長遠(yuǎn)發(fā)展，近年來，引進(jìn)相關(guān)技術(shù)專業(yè)人才和消化國外先進(jìn)的技術(shù)，不斷進(jìn)行產(chǎn)品和技術(shù)的更新改進(jìn)，同時(shí)，完善的質(zhì)量保證體系，提高企業(yè)的整體管理水平，一切努力和付出，惟愿助您一臂之力。
詳情介紹：
中文名稱： UBAP2L 抗原（重組蛋白）

英文名稱： UBAP2L Antigen (Recombinant Protein)

別     名：  ubiquitin associated protein 2-like; NICE-4

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to C terminal 200 amino acids of human UBAP2L

技術(shù)規(guī)格

Full name:

ubiquitin associated protein 2-like

Synonyms:

NICE-4

Swissprot:

Q14157

Gene Accession:

BC003170

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

UBAP2L, also known as NICE4, is a protein that is ubiquitously expressed. Phosphorylated upon DNA damage, NICE4 contains one UBA domain and is expressed as 4 isoforms produced by alternative splicing events. The gene that encodes NICE4 maps to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.







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