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  • 產(chǎn)品名稱：ZNF131 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
ZNF131 抗原（重組蛋白）奉行以人為本、唯才善用，提倡人是核心資本，公平合理并創(chuàng)造性地使用人才，盡可能的給員工提供足夠的舞臺去發(fā)揮去成長，公司尊重人，尊重每一位員工的個性，依托這樣的人才觀，將進一步完善科學合理的人力資源管理機制，造就一個良好的人才成長空間。
詳情介紹：
中文名稱： ZNF131 抗原（重組蛋白）

英文名稱： ZNF131 Antigen (Recombinant Protein)

別     名：  zinc finger protein 131; ZBTB35; pHZ-10

相關類別： 抗原

儲     存：  冷凍（-20℃） 

概     述

Fusion protein corresponding to a region derived from 424-623 amino acids of human ZNF131

技術規(guī)格

Full name:

zinc finger protein 131

Synonyms:

ZBTB35; pHZ-10

Swissprot:

P52739

Gene Accession:

BC035875

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the ***** central nervous system. ZNF131 also represses ER? (Estrogen receptor alpha)-mediated transactivation by interrupting ER? binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events.






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