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  • 產(chǎn)品名稱：ZNF281 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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ZNF281 抗原（重組蛋白）關(guān)抗體在生物行業(yè)的發(fā)展國家給予了極大的重視，更多地側(cè)重于科研的投入，服務(wù)和業(yè)務(wù)在同行獲得一致好評(píng)，其立足于生命科學(xué)領(lǐng)域，全力打造高品質(zhì)生物科技產(chǎn)品鏈和技術(shù)服務(wù)鏈，也具備豐富的管理經(jīng)驗(yàn)。
詳情介紹：


中文名稱： ZNF281 抗原（重組蛋白）

英文名稱： ZNF281 Antigen (Recombinant Protein)
 
別     名：  zinc finger protein 281; ZBP-99; ZNP-99

相關(guān)類別： 抗原

儲(chǔ)     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 696-895 amino acids of human ZNF281

技術(shù)規(guī)格

Full name:

zinc finger protein 281

Synonyms:

ZBP-99; ZNP-99

Swissprot:

Q9Y2X9

Gene Accession:

BC060820

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.




 




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