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  • 產品名稱：ZNF354A 抗原（重組蛋白）

  • 產品型號：1mg
  • 產品廠商：通蔚生物
  • 產品價格：3580
  • 產品庫存：35
  • 產品文檔：
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ZNF354A 抗原（重組蛋白）關抗體在生物行業(yè)的發(fā)展國家給予了極大的重視，更多地側重于科研的投入，服務和業(yè)務在同行獲得一致好評，其立足于生命科學領域，全力打造高品質生物科技產品鏈和技術服務鏈，也具備豐富的管理經驗。
詳情介紹：


中文名稱： ZNF354A 抗原（重組蛋白）

英文名稱： ZNF354A Antigen (Recombinant Protein)

別     名：  zinc finger protein 354A; EZNF; HKL1; KID1; KID-1; TCF17; HEL104

相關類別： 抗原

儲     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 406-605 amino acids of human ZNF354A

技術規(guī)格

Full name:

zinc finger protein 354A

Synonyms:

EZNF; HKL1; KID1; KID-1; TCF17; HEL104

Swissprot:

O60765

Gene Accession:

BC047105

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the ***** kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.






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