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  • 產(chǎn)品名稱：AGR3 抗原（重組蛋白）

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詳情介紹：
中文名稱： AGR3 抗原（重組蛋白）

英文名稱： AGR3 Antigen (Recombinant Protein)

別     名：  Anterior gradient 3 homolog (Xenopus laevis); AG3; HAG3; hAG-3; BCMP11; PDIA18

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：
 
Fusion protein corresponding to a region derived from 22-166 amino acids of human AGR3
   
技術(shù)規(guī)格

Full name:

Anterior gradient 3 homolog (Xenopus laevis)

Synonyms:

AG3; HAG3; hAG-3; BCMP11; PDIA18

Swissprot:

Q8TD06

Gene Accession:

BC058284

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene. The deduced 166-amino acid protein has an N-terminal signal sequence. Fluorescence-tagged BCMP11 localized in secretory or endosome-like organelles in transfected breast carcinoma cell lines. Immunohistochemical analysis showed that expression of BCMP11 was restricted in normal tissues, with significant staining of only the epithelial lining of colonic mucosa. However, BCMP11 was detected in 43 of 58 (74%) breast cancer tissues tested, but not in normal breast ductal epithelial cells. In cancerous epithelial cells, BCMP11 localized to the cytoplasm.






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