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  • 產(chǎn)品名稱：ARHGEF3抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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ARHGEF3抗原（重組蛋白）擁有上百名專業(yè)的技術(shù)人員，為您提供專業(yè)、耐心的服務(wù)，我們專業(yè)，所以值得信賴，信奉“客戶至上”“誠信chuang新”；將竭盡所能，為您提供*便捷、*專業(yè)的采購服務(wù)，節(jié)省您的時間和成本。同時，完善的質(zhì)量保證體系，提高企業(yè)的整體管理水平，一切努力和付出，惟愿助您一臂之力。
詳情介紹：


中文名稱： ARHGEF3抗原（重組蛋白）

英文名稱： ARHGEF3 Antigen (Recombinant Protein)

別     名：  GEF3; STA3; XPLN

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to N terminal 202 amino acids of human ARHGEF3

技術(shù)規(guī)格

Full name:

Rho guanine nucleotide exchange factor (GEF) 3

Synonyms:

GEF3; STA3; XPLN

Swissprot:

Q9NR81

Gene Accession:

BC099715

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.






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