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  • 產(chǎn)品名稱(chēng):CRK抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫(kù)存:35
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詳情介紹:
中文名稱(chēng): CRK抗原(重組蛋白)

英文名稱(chēng): CRK Antigen (Recombinant Protein)

別     名:  p38; CRKII
 
儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概     述:

Fusion protein corresponding to a region derived from C terminal 103 amino acids of human CRK

技術(shù)規(guī)格

Full name:

v-crk avian sarcoma virus CT10 oncogene homolog

Synonyms:

p38; CRKII

Swissprot:

P46108

Gene Accession:

BC009837

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.





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