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  • 產(chǎn)品名稱：ELOB抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
ELOB抗原（重組蛋白）公司秉承“專注品質、信守承諾、積極溝通、chuang新服務”的企業(yè)文化積極參與生物領域的技術chuang新和技術服務，力求為我國科研事業(yè)添磚加瓦，嚴格的質控體系，建立和完善企業(yè)制度，創(chuàng)造性發(fā)展，客戶的滿意就是我們的宗旨。
詳情介紹：
中文名稱： ELOB抗原（重組蛋白）

英文名稱： ELOB Antigen (Recombinant Protein)

別     名：  SIII; TCEB2

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 1-118 amino acids of human ELOB

技術規(guī)格

Full name:

elongin B

Synonyms:

SIII; TCEB2

Swissprot:

Q15370

Gene Accession:

BC013306

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]





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