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  • 產(chǎn)品名稱:GAB2抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:
中文名稱: GAB2抗原(重組蛋白)

英文名稱: GAB2 Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to C terminal 250 amino acids of human GAB2

技術(shù)規(guī)格

Full name:

GRB2-associated binding protein 2

Swissprot:

Q9UQC2

Gene Accession:

BC131711

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.





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