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  • 產(chǎn)品名稱：GPM6A抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：
中文名稱： GPM6A抗原（重組蛋白）

英文名稱： GPM6A Antigen (Recombinant Protein)

別     名：  M6A; GPM6

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 149-278 amino acids of human GPM6A

技術(shù)規(guī)格

Full name:

glycoprotein M6A

Synonyms:

M6A; GPM6

Swissprot:

P51674

Gene Accession:

BC022508

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.





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