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  • 產(chǎn)品名稱：LSM11 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
LSM11 抗原（重組蛋白）始終以服務國內先進的研究機構和國內高校為己任，在不懈的探索和實踐中，長期以來一直注重品牌建設，始終把抓產(chǎn)品質量作為所有工作的重中之重，所生產(chǎn)銷售的各類試劑受到廣大用戶的廣泛認可和信賴。有關的一切操作和事項，都嚴格依照步驟依據(jù)，為了保護結果真實有效，應該以英文版說明書為準。
詳情介紹：



中文名稱： LSM11 抗原（重組蛋白）

英文名稱： LSM11 Antigen (Recombinant Protein)

別     名：  LSM11, U7 small nuclear RNA associated

相關類別： 抗原

儲     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 161-360 amino acids of human LSM11

技術規(guī)格

Full name:

LSM11, U7 small nuclear RNA associated

Swissprot:

P83369

Gene Accession:

BC126449

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Sm and Sm-like (LSm) proteins form donut-shaped, ubiquitously expressed heptameric complexes that are involved in various steps of RNA metabolism, including RNA-protein interactions and structural changes that are required during ribosomal subunit assembly. LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.






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