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  • 產(chǎn)品名稱：LSM10 抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
LSM10 抗原（重組蛋白）始終以服務國內(nèi)先進的研究機構和國內(nèi)高校為己任，在不懈的探索和實踐中，長期以來一直注重品牌建設，始終把抓產(chǎn)品質量作為所有工作的重中之重，所生產(chǎn)銷售的各類試劑受到廣大用戶的廣泛認可和信賴。有關的一切操作和事項，都嚴格依照步驟依據(jù)，為了保護結果真實有效，應該以英文版說明書為準。
詳情介紹：


中文名稱： LSM10 抗原（重組蛋白）

英文名稱： LSM10 Antigen (Recombinant Protein)

別     名：  LSM10, U7 small nuclear RNA associated; MST074; MSTP074

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-123 amino acids of human LSM10

技術規(guī)格

Full name:

LSM10, U7 small nuclear RNA associated

Synonyms:

MST074; MSTP074

Swissprot:

Q969L4

Gene Accession:

BC007623

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.





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